A German-Baroque Laboratory in the Aichi Countryside

The man who built this building now looks out from Japan's 1,000-yen note. Kitasato Shibasaburo, born in 1853 in what is today Kumamoto Prefecture, studied bacteriology in Berlin under Robert Koch, isolated the tetanus bacillus, and helped invent serum therapy. When he needed a home for his own research institute, he did not commission a fashionable Tokyo landmark. He asked for something that recalled the German laboratory where his career began.

The result was completed in 1915 in Shirokane, in central Tokyo: a two-storey timber building dressed in German Baroque, with a steep gambrel roof of natural slate and a stepped gable rising over the entrance. It stood in the capital for more than sixty years. In 1979 it was carefully taken apart, and in 1980 it was rebuilt some 350 kilometers west, at the open-air architecture museum of Meiji-mura in Inuyama, Aichi Prefecture, where it stands today.

The building reads as a piece of Meiji-and-Taisho ambition: a young nation borrowing European forms to house European science, then quietly adapting them. Geometric ornament around the windows hints at the design currents that were just then arriving from the continent.

Why It Is Protected, and at What Level

It helps to be precise about its status. This is not a National Treasure, nor an Important Cultural Property. It is a Registered Tangible Cultural Property (Building), entered on the national register on December 1, 2003, under registration number 23-0079. Registration is a lighter form of protection than designation. It was introduced in 1996 to safeguard the enormous stock of modern buildings that fall outside the stricter designation system, and it asks owners to preserve a structure while allowing more everyday use.

The building was registered under the criterion that it serves as a model of design. In plain terms: it is a well-preserved, characterful example of how early twentieth-century Japan handled Western timber architecture. Its value lies less in rarity than in the clarity with which it shows a moment in Japanese architectural history, and in its link to one of the country's foundational scientists.

One detail worth knowing for anyone reading the official record: the structure is counted as a single building (one tou), with a floor area of about 360 square meters, a slate roof partly finished in copper, and a small rooftop tower.

What to Look For

Start with the roofline. The gambrel form, where each slope changes pitch partway down, is laid with thin sheets of natural slate quarried and split from stone, and broken by comb-shaped dormer windows that light the attic. A taller central section carries a small octagonal tower. Above the porch sit the two signatures of the design: a stepped, tiered gable and that octagonal spire.

Come closer and the timber detailing rewards a slow look. The walls are clad in horizontal clapboard, while the wainscot below and the narrow band beneath the eaves switch to vertical boarding. Pilasters frame the sash windows, which slide up and down in the manner of the period. The entrance porch is held up by square columns cut with vertical grooves, finished with a low parapet.

There is a practical logic hidden in the plan. The principal rooms were placed on the north side of the building. North light changes little through the day, which gave the researchers the steady illumination they needed to work at their microscopes. It is a reminder that this was a working laboratory before it was a museum piece.

Inside, the building now serves as the Kitasato Institute Main Building and Hall of Medicine. Its permanent exhibition, renewed in May 2024 to mark Kitasato's appearance on the new banknote, traces his life and the early history of infectious-disease research in Japan. The second-floor laboratory, long closed, has been opened to visitors.

Around the Site

Meiji-mura is the destination, not just the building. Spread across a hillside above Lake Iruka, the museum has gathered more than sixty structures from the Meiji and Taisho eras, several of them designated cultural properties in their own right. The reassembled front entrance hall of Frank Lloyd Wright's Imperial Hotel is the headline piece, and a vintage steam locomotive and streetcar run within the grounds. Allow most of a day; the site is large and walking between buildings takes time.

Inuyama itself is worth the trip. A short distance away stands Inuyama Castle, whose keep is one of only a handful in Japan to hold National Treasure status and one of the oldest surviving. The old castle town below it has been revived with teahouses and craft shops.

Meiji-mura sits a bus ride from Inuyama Station, reached in roughly half an hour by limited express from Nagoya on the Meitetsu line. Opening days and hours vary by season, and the museum occasionally closes for maintenance, so it is wise to check the official calendar before setting out.

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Q&A

QIs this the original building, and is it really in its original location?
AIt is the original 1915 structure, but not on its original site. It was built in Shirokane, Tokyo, then dismantled in 1979 and rebuilt at Meiji-mura in 1980. The relocation is part of its story rather than a flaw.
QCan I go inside?
AYes. The building is open to the public as part of Meiji-mura and houses an exhibition on Kitasato Shibasaburo. Entry is included with museum admission. The previously closed second-floor laboratory can now be seen.
QWho was Kitasato Shibasaburo?
AA pioneering bacteriologist who trained under Robert Koch in Germany, isolated the tetanus bacillus, and advanced serum therapy. He founded the institute this building once served. Since 2024 his portrait has appeared on Japan's 1,000-yen note.
QWhy does it look German?
AKitasato modeled it on the German research institute where he had studied. The German Baroque styling, with its gambrel roof and stepped gable, was a deliberate nod to the place that shaped his science.
QHow long should I plan for a visit?
ABudget half a day to a full day for Meiji-mura as a whole. The museum is large, with more than sixty buildings spread over a hillside, and getting between them on foot or by its period transport takes time.

Basic Information

NameMeiji-mura Kitasato Institute Main Building (Meijimura Kitazato Kenkyujo Honkan)
Location1 Uchiyama, Inuyama, Aichi Prefecture (within Museum Meiji-mura)
DesignationRegistered Tangible Cultural Property (Building); registration no. 23-0079
Registration dateDecember 1, 2003
Built / Relocated1915 (Taisho 4) in Tokyo; relocated to Meiji-mura in 1980
StructureTwo-storey timber, natural slate roof partly clad in copper, floor area approx. 360 m², with rooftop tower
Count1 building
OwnerMeiji-mura Foundation
AccessInside Meiji-mura, open to the public with museum admission

References

National Database of Designated Cultural Properties (Agency for Cultural Affairs)
https://kunishitei.bunka.go.jp/bsys/maindetails/101/00003666
Cultural Heritage Online (National Institutes for Cultural Heritage)
https://bunka.nii.ac.jp/heritages/detail/179886
Kitasato Institute Main Building and Hall of Medicine (Museum Meiji-mura)
https://www.meijimura.com/sight/北里研究所本館・医学館/
Minato City People of Note Database: Kitasato Institute
https://www.lib.city.minato.tokyo.jp/yukari/j/bld-detail.cgi?id=46

Last verified: 2026.06.17